CBD can be a natural option to support your pets’ daily routine. If you’re new to giving CBD to your cat, you might be wondering: How long does it stay in their system — and what’s the right amount to use?

Let's break it down so you can better understand the onset, effects, duration, and dosing of CBD for cats.

How Long Does CBD Last in a Cat?

Generally, CBD can remain in a cat’s system for between 4 to 48 hours, depending on several factors, including the dose, delivery method, metabolism, and overall health.

Lower doses — around 0.1 to 0.25 mg per pound — typically produce effects that last 4 to 8 hours. Moderate to higher doses, ranging from 0.25 to 0.5 mg per pound, may last longer, from 12 to 24 hours, and sometimes up to 48 hours.

How quickly CBD takes effect also depends on how it's administered. 

CBD oil, whether placed under the tongue or mixed into food, usually begins working within 15 to 45 minutes. On the other hand, CBD treats or chews may take a bit longer to kick in, typically around 45 to 60 minutes as it has to be digested before it’s absorbed. Cats are on the pickier side regarding their eating preferences, so it can be smart to play around with options before committing to a bulk order of any CBD product. 

You’ll know it’s working when your cat becomes calmer, less reactive to stress, more mobile, or regains interest in food or play. These effects aren’t guaranteed as CBD affects individual cats uniquely; however, testimonials and limited research make these effects seem common.

What Is the Longest CBD Will Stay in My Cat’s System?

In rare cases — especially with larger doses or slow metabolisms — CBD may stay in your cat’s system for up to 48 hours. But this doesn’t mean your cat will feel the effects for two full days.

Most cats process CBD relatively quickly, and the effects will gradually taper off over the course of 12–24 hours. That’s why many CBD products recommend once or twice daily dosing for best results.

How Much CBD Should I Give My Cat?

The correct CBD dosage depends on your cat’s weight, age, and health condition. Here’s a general rule of thumb:

• Mild support: 0.1–0.25 mg CBD per lb of body weight

• Moderate to severe support: 0.25–0.5 mg CBD per lb of body weight
  
  

For example, a 10 lb cat might start with 1–2.5 mg CBD for mild symptoms and go up to 5 mg for more intense support.

Always start with a lower dose and increase gradually, especially if your cat is sensitive or new to CBD. Monitoring behavior changes within the first few hours will give you a good idea of how they respond.

Online Experiences: How Long Does CBD Last for Other Cats?

Across Reddit threads, cat wellness groups, and product reviews, most users report that CBD lasts between 6 and 12 hours in their cats, depending on the brand and dose.

“My senior cat gets CBD for her arthritis and we dose twice a day—morning and night. She moves more easily about 30 mins after the dose and is good most of the day.” – Reddit user

“I give my anxious rescue cat CBD treats once every 24 hours and it keeps her mellow without making her sleepy.”– Facebook group

“I give it to my cat at night because he get hyper and pounces on me in my sleep and meows all night. Thanks to this he relaxes and sleeps throughout the night.”– Product review of our Broad Spectrum CBD Oil for Cats

What to Know About CBD Duration in Cats

So, how long does CBD last in cats? On average, expect the effects to last 4–12 hours, though trace amounts may remain in the body for up to 48 hours. Proper dosing, consistent use, and observing your cat’s behavior are key to getting the most from CBD.

Always use high-quality, THC-free CBD made specifically for pets, and consult your vet if you’re unsure where to start.

If you're considering CBD for your cat, the safest route is to start low, observe, and adjust — just like many cat parents successfully do every day.